Shimadzu LC-2010CHT Integrated High Performance Liquid Chromatography (HPLC) System

The Shimadzu LC-2010CHT HPLC System is an integrated High Performance Liquid Chromatography instrument designed for advanced analytical laboratories, pharmaceutical research facilities, chemical industries, biotechnology laboratories, and quality control departments. Developed by Shimadzu, this system combines multiple essential liquid chromatography components into a compact and automated analytical platform. It is designed to support reliable, reproducible, and efficient chromatographic analysis across a wide range of laboratory applications.

The Shimadzu LC-2010CHT belongs to the LC-2010HT series of integrated high-throughput liquid chromatography systems. It incorporates several essential analytical modules, including a solvent delivery pump, online degasser, autosampler, sample cooler, column oven, mixer, and UV-Visible detector. The integrated configuration helps simplify laboratory operations by reducing the need for separately installed modules and allowing users to manage multiple analytical functions through a centralized control panel.

One of the important features of the LC-2010CHT is its automated sample injection system. The autosampler is designed to handle multiple sample vials and supports automated injection sequences, helping laboratories process numerous samples with reduced manual intervention. Its refrigerated sample cooling facility helps maintain suitable sample temperatures during analytical sequences, making it useful when working with temperature-sensitive compounds.

The instrument incorporates a precision solvent delivery system with a serial dual-plunger pump. It supports flow rates ranging from 0.001 to 5.0 mL/min and can operate with a low-pressure gradient solvent delivery configuration supporting up to four solvents. This allows analysts to develop and execute different chromatographic methods depending on the chemical properties of the target compounds and the requirements of the analytical procedure.

The integrated online degassing unit helps remove dissolved gases from the mobile phase before they enter the pumping system. Removing dissolved air helps minimize bubble formation, detector signal disturbances, and other problems associated with gas interference during chromatographic analysis. This contributes to more stable chromatographic operation.

Another important component is the integrated column oven, which provides controlled temperature conditions for chromatographic separation. Temperature regulation helps improve retention-time consistency and supports analytical methods that require controlled column temperatures. The system can accommodate two 250 mm columns, providing flexibility for different chromatographic applications.

The LC-2010CHT also incorporates a UV-Visible detector with a deuterium lamp source. The detector offers a wavelength range of 190–600 nm, enabling the detection and quantification of many compounds that absorb ultraviolet or visible radiation. Its dual-wavelength monitoring capability allows analysts to monitor two selected wavelengths, depending on the configured analytical method.

The front control panel features an LCD display and dedicated operating keys for managing instrument functions. Users can configure analytical parameters, control the pump, manage injection sequences, adjust detector settings, and operate the column oven. The integrated controller helps simplify routine laboratory operations.

The Shimadzu LC-2010CHT is suitable for pharmaceutical formulation analysis, drug development, chemical testing, food and beverage analysis, environmental monitoring, biochemical research, and quality assurance applications. It can support analytical techniques such as reversed-phase chromatography and other compatible liquid chromatography methods.

For pharmaceutical manufacturers, this instrument can be used in research and development, raw material testing, finished product analysis, stability studies, and routine quality control. Research laboratories can use it for the separation, identification, and quantification of chemical compounds in complex samples.

The compact integrated design, automated sample handling, controlled temperature environment, precision solvent delivery, and UV-Visible detection make the Shimadzu LC-2010CHT a valuable analytical instrument for laboratories requiring dependable HPLC capabilities.

This system is particularly suitable for laboratories looking for an integrated HPLC platform for routine analytical testing, research activities, and pharmaceutical quality control.

2.2. Applications of Product

• Pharmaceutical drug formulation analysis.

• Active Pharmaceutical Ingredient (API) testing.

• Pharmaceutical quality control and quality assurance.

• Drug purity and impurity profiling.

• Stability testing of pharmaceutical products.

• Chemical compound separation and identification.

• Food and beverage quality analysis.

• Environmental sample analysis.

• Biotechnology and biochemical research.

• Natural product and herbal extract analysis.

• Research and development laboratories.

• Academic and industrial analytical laboratories.

2.3. Key Features of Product

1. Integrated HPLC system with multiple analytical modules.

2. Automated sample injection and analysis.

3. Refrigerated autosampler with sample cooling.

4. Precision dual-plunger solvent delivery pump.

5. Low-pressure gradient system supporting up to four solvents.

6. Integrated online membrane degasser.

7. Temperature-controlled column oven.

8. UV-Visible detector with deuterium lamp.

9. Wavelength range of 190–600 nm.

10. Dual-wavelength monitoring capability.

11. User-friendly LCD control panel.

12. Automated analytical sequence management.

13. Suitable for pharmaceutical and chemical analysis.

14. Supports high-throughput laboratory workflows.

2.4. Technical Specifications

Specifications are based on the LC-2010CHT manufacturer's documentation. Optional configurations may vary.

2.5. Product Condition

Condition: To be confirmed

• Brand New – If supplied unused.

• Refurbished – If professionally refurbished and tested.

• Used – If supplied in working used condition.