Teledyne Isco RediSep Rf Normal Phase Disposable Flash Chromatography Columns, 4 g, Pack of 20

The Teledyne Isco RediSep Rf Normal Phase Disposable Flash Chromatography Column is a laboratory consumable designed for the separation and purification of chemical compounds using flash chromatography. The product contains a silica-based stationary phase and is intended for normal-phase chromatographic separations. According to the product label, each column has a 4-gram capacity, and the package contains 20 columns. The catalog number printed on the packaging is 69-2203-304.

HC21

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Flash chromatography is widely used in organic chemistry, pharmaceutical research, natural product chemistry, and chemical development laboratories. It separates components of a mixture according to their different interactions with a stationary phase and a flowing mobile phase. By selecting suitable solvents and operating conditions, researchers can isolate desired compounds from reaction mixtures, crude extracts, and other complex samples.

The RediSep Rf normal-phase column uses silica as its stationary phase. In normal-phase chromatography, relatively polar silica interacts differently with individual compounds, helping separate them as the mobile phase passes through the column. Differences in polarity and adsorption behavior influence the retention and elution of compounds. This makes silica-based flash columns useful for a broad range of organic purification workflows.

These disposable columns are designed for use with compatible flash chromatography systems. Their prepacked format helps simplify laboratory preparation by providing a ready-to-use chromatographic bed, reducing the need to pack individual columns manually. The consistent column format also supports repeatable purification workflows when appropriate methods, solvents, sample loads, and operating conditions are maintained.

HC21

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The 4-gram silica capacity is intended for relatively small-scale purification work. The manufacturer's column information provides different recommended sample loads depending on the difficulty of separation. For difficult separations, a lower sample load is generally appropriate, while easier separations may allow higher loading. The correct loading amount should therefore be determined from the compound mixture and the separation method rather than from the silica capacity alone.

HC21

Typical laboratory workflows may include purification of organic synthesis products, isolation of target compounds from natural extracts, removal of impurities from reaction mixtures, and preliminary purification before further analytical or preparative procedures. Researchers may use the columns during method development, compound screening, medicinal chemistry projects, and small-scale chemical synthesis. Suitability depends on the chemical properties of the sample and the solvent system.

The disposable design is particularly useful when laboratories want to avoid packing columns manually or when they prefer a fresh stationary phase for each purification. Single-use columns can also help reduce the risk of cross-contamination between unrelated samples, provided that appropriate laboratory handling and disposal procedures are followed.

The pictured packaging identifies the product as RediSep Rf, Normal Phase, 4 gram, with catalog number 69-2203-304 and lot number 221318-201W. The package appears to have been stored for some time, and the label shows visible dirt and wear. These observations do not establish whether the columns are unused, whether the original packaging seal is intact, or whether the stationary phase remains within its intended storage conditions.

Before use, the buyer should verify the package seal, storage history, product integrity, lot information, and compatibility with the intended flash chromatography system. The columns should be used according to the manufacturer's instructions and the applicable chemical safety procedures.

Overall, the Teledyne Isco RediSep Rf 4-gram normal-phase disposable flash chromatography column is a useful consumable for small-scale compound purification in research and development laboratories. Its prepacked silica format and package of 20 columns make it suitable for laboratories performing repeated purification experiments, provided the product's condition and suitability are confirmed.

2.2 Applications of the Product

• Organic synthesis: Purification of compounds produced during chemical reactions.

• Pharmaceutical research: Small-scale purification of research compounds and synthetic intermediates.

• Natural product chemistry: Separation of compounds from plant and other natural extracts.

• Research and development: Isolation of target compounds during method development.

• Chemical laboratories: Removal of impurities from crude reaction mixtures.

• Medicinal chemistry: Purification of compounds prepared during discovery research.

• Analytical method development: Preliminary sample purification before further analysis.

• Academic research: Practical chromatographic separations in chemistry laboratories.

2.3 Features of the Product

• Manufactured under the Teledyne Isco RediSep Rf product line.

• Normal-phase chromatography format.

• Prepacked silica stationary phase.

• 4-gram column size.

• Pack of 20 disposable columns.

• Designed for flash chromatography purification.

• Silica particle size of approximately 40–63 µm.

• Single-use design.

• Suitable for compatible flash chromatography systems.

• Manufacturer catalog number 69-2203-304.

  

  HC21

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2.4 Technical Specifications

The technical specifications above are based on the manufacturer's product information for the corresponding 4-gram catalog number.

Package – Teledyne ISCO

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